Relationship of Growth Performance and Metabolite Profile of Broiler  Chickens with the Supplementation of Probiotics Bacillus coagulans and Lactobacillus plantarum

Eigmon Indra Pradhika; Rika Indri Astuti; Anja Meryandini

doi:10.14334/jitv.v30i1.3453

Relationship of Growth Performance and Metabolite Profile of Broiler Chickens with the Supplementation of Probiotics Bacillus coagulans and Lactobacillus plantarum

Eigmon Indra Pradhika, Rika Indri Astuti, Anja Meryandini

DOI

https://doi.org/10.14334/jitv.v30i1.3453

Abstract

Probiotic supplementation is an alternative to Antibiotics Growth Promotor. The probiotics L. plantarum and B. coagulans are known to improve the growth performance of broiler chickens. Information regarding the metabolite results of these two probiotics with their hosts is still limited. This study aims to provide information regarding the metabolite profile resulting from probiotic supplementation which is associated with the growth performance of chickens. A total of 120 Ross 308 Broilers were given a treated diet with Negative Control (NC), L. plantarum (LP), B. coagulans (BC), and B. coagulans mixed with L. plantarum (BCLP). The growth performance parameter evaluated was the mean Body Weight (mean BW), adjustment Feed Convertion Ratio (adjFCR), cumulative Feed Intake (cumFI) and Performance Efficiency Factor (PEF). Metabolomic analysis was carried out using the untargeted metabolite profiling method on cecum samples consisting of broad spectrum compound analysis and volatile compound analysis. Analysis of differences in growth performance resulted in only the meanBW parameter being significantly different (p?0.05). Meanwhile, other performance parameters, adjFCR, cumFI, and PEF, do not provide any significant difference (p?0.05). The important differentiating metabolites between treatment are acetic acid, lactic acid, butanoic acid, 1-octadecanol, and palmitic acid. Metabolites that can be stated as differentiating metabolites between LP and BC are acetic acid, lactic acid, and butanoic acid. Meanwhile, metabolites that can be declared as differentiating metabolites are lactic acid as a differentiator for good meanBW performance and 1-octadecanol and palmitic acid as differentiators without probiotic supplementation.

Keywords

probiotics; metabolite; meanBW; differentiating metabolites

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